Arthritis :: Leflunomide Generic

Leflunomide Generic

US Brand Name Arava
Generic Name Leflunomide
Other Brand Name LEFRA, Lefumide
Manufacturer TORRENT, Cipla
Packing 10
Form Tabletlet
Strength 20 mg, 10 mg
 
10 mg $0.89
20 mg $1.79
Quantity Tabletlet
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Introduction

Arava is a drug of choice for arthritis. It is being used for two decades now. This drug is safe to use by general public. It alleviates the pain by means of decreasing the inflammation of the joint. The generic name for this drug is leflunomide. This medicine is manufactured by TORRENT and Cipla. Other popular trade names are LEFRA and Lefumide. This is the perfect drug to treat any forms of arthritis.

Composition

Leflunomide which is the major component of Arava is a pyrimidine inhibitor. Lactose monohydrate, crospovidone, colloidal silicon dioxide, talc, magnesium stearate, titanium oxide, starch, and ferric oxide are the inactive ingredients of this drug. For your information this drug is taken orally.

Use

This medication is primarily use to treat rheumatoid arthritis especially of those involving the cartilage of the joint. As of the statistics, female are more prone to arthritis in comparison with the male. Its effect is to primarily reduce the symptoms brought about by the disease. Using this drug will improve the physical functionality overall. Recently, Arava is also being used for treating liver and hematologic conditions.

Dosage and administration

The ideal dosing interval for arthritic patient is 24 hours. Arava medication can be given initially with a dose of 100 mg daily for three days straight. For maintenance therapy, this can be given with a loading dose of 20 mg. A much higher dose is said to have more side effects to patient. However, dosing will be adjusted gradually depending on the patient’s tolerance and response to Arava therapy. This drug comes in a tablet form. It is very important to abide with the doctor’s prescription to attain maximum health benefit while undergoing this therapy.

Contraindication

Usage of this drug is contraindicated to patient with known sensitivity reaction to Arava drug and its component. Pregnant woman is discouraged to use this drug as it may cause fetal defects on the child. If you have any severe disease condition such as hepatitis B, kidney disease, hepatitis C, tuberculosis either active or inactive, anemia, or fungal infection, then you are not also allowed to use this medication. Report any past medical history of previous hospitalizations to your health care provider to assess properly your disease condition.

Important Precautions

Chronic use of this medication may cause hepatotoxiity. So, it is very important to follow the dos and don’ts in taking this medication. Severe skin reaction such as allergy may take place. If this happens stop the usage of the drug and seek medical attention right away. Malignancy will also occur when this drug is use for a prolonged period of time. Women specifically lactating mother and pregnant woman should take cautious in taking this drug as it may cause fetal defects.

Side effects

The ill effects of using Arava are alopecia or hair loss and appearance of rash. You can also have hernia, body malaise or general body weakness, pelvic pain, diarrhea, fever, jaundice or yellowing of the skin, infection, allergic like reaction. Severe side effects that needs medical attention right away are chest tightness, inflammation of the lips and tongue, and inflammation of other part of the face in general, elevation of liver enzymes, palpitation, vertigo with excessive sweating, espistaxis or bleeding of the nose, appearance of acne, and vaginal moniliasis. There are also side effects that rarely experience by the patient such as severe infection that can lead to sepsis that can eventually lead to death, peripheral neuropathy, hepatitis, angioedema, and stevens –Johnson like syndrome.

storage

To ensure the maximum shelf life of this drug it is important to keep or store the drug as recommended in the drug literature. Do not place Arava in temperature above 25 degree Celsius. Always place the drug in its original container and see to it that it is close tightly. Do not store the medication in the comfort or bath room. Discard immediately if it reached expiration.
 

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