Diabetes :: Pioglitazone/ Metformin Tablets

Pioglitazone/ Metformin Tablets

US Brand Name ACTOplus
Generic Name Pioglitazone/ XR Metformin
Other Brand NameBiodub-M
Packing10
Manufacturer SUN PHARMACEUTICALS, Franco Indian
Form Tablets
Strength 15 mg/ 500 mg, 30 mg/ 500 mg
 
15 mg/ 500 mg $0.41
30 mg/ 500 mg (Franco Indian) $0.89
Quantity Tablets
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Introduction

Pioglitazone being an Actoplus is actually a pioglitazone hydrochloride, an oral tablet acts as ant diabetic agent that reduces insulin resistance. Medical studies revealed that this medicine help increase insulin sensitivity in the body of the person who has a non-insulin-dependent diabetes mellitus because of its active content. Octoplus with a generic name of Biodub which is a kind ofpioglitazone from the manufacturer, SUN PHARMACEUTICALS in Franco Indian helps treat type 2 diabetes or young-on set diabetes.

Composition

ACTOplus is composed of pioglitazone hydrochloride and metformin hydrochloride along with inactive ingredients such as hypromellose 2910 USP, povidone USP, titanium dioxide USP, croscarmellose sodium NF, microcrystalline cellulose NF, polyethylene glycol 8000 NF, magnesium stearate NF and talc USP. Pioglitazone and metformin are both crystalline powder but only metformin is water soluble. Pioglitazone is soluble in dimethylformamide but definitely not in water. This medicine is to be taken orally.

Use

Presently, this is use to lessen the transformation of diabetes fromprediabetic stage to type 2 diabetes by almost 72%. There is an approximate rate of 15% to 30% dosage of this drug found in urine upon taken its oral administration.

Dosage and administration

This drug starts on a dosage of 500 mg two times a day or a total of 850 mg once every day. It will increase gradually for 500 mg per week or 850 mg every two weeks as tolerable medication on the basis of the body response on glucose levels. Maximum dose is 2550 mg good for three days through dividing the doses. Using extended tablets, begin in 500mg or 1000 mg per day every dinner. It will increase on 500 mg per week to a maximum dose of 2000mg or 25000 for Fortamet just once per day or divide into two doses. Pediatric patients aging 10-16 years old can start taking it for 500 mg two times a day.

Contraindication

Patients with hypersensitivity in using pioglitazone cannot use this drug medicine or any other part of its medicinal forms especially thiazolidinediones. There is also a great restriction for those who have heart ailment/s.

Important Precautions

It can also activate the ovulation cycle of female patients who is at big risk on pregnancy for those women taking the oral contraception.

Side effects

This XR Metformin tablets is capable of fluid retention in the body of the patients. Patients can also experience peripheral edema, suffer from anemia, mild gaining of weight and increase the tendency to feel a headache, suffer on dental problems, sinusitis, myalgia and acquire the upper respiratory tract infection so the physician should check their patients.

storage

This is usually packed with 10 tablets content per pack and the user must keep this medicine away from the children and safety in a place not direct from the heat of the sun yet it's cool and dry.
 

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